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Dr. Sylvia Asa
Dr. Sylvia Asa is an Endocrine Pathologist at University Health Network and Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto.
A Clinician-Scientist with a focus on Endocrine Pathology, her research aims to identify the basis for development of endocrine tumors, to improve diagnostic tests and to identify targets for therapy of those diseases. She has published more than 400 scientific articles, written 4 books, co-edited 5 books and written more than 100 book chapters.
Dr. Asa has served as President of the Endocrine Pathology Society (1997-1998) and the US-Canadian Academy of Pathology (2005-06). She has been the recipient of many awards and honors, including the Arthur Purdy Stout Society of Surgical Pathologists, the Novartis Canada Senior Scientist Award, the Professor C.F.A. Culling Memorial Lecture Award of the National Society for Histotechnology, the ICRF Woman of Action Award, the F.K. Mostofi Distinguished Service Award of the US-Canadian Academy of Pathology, and honorary fellowship in the Royal College of Pathologists, as well as several teaching awards from the University of Toronto.
As head of the largest academic pathology department in Canada from 2000 through 2015, Dr. Asa has made innovative changes to the practice of the discipline, with emphasis on subspecialization, automation, biobanking, electronic initiatives and digital pathology. To ensure public knowledge of the role of Pathology and maintain a direct connection with patients, Dr. Asa is also a consultant to several patient groups.
Dr. Sylvia Asa
Dr. Shereen Ezzat, MD, FACP, FRCPC
Senior Scientist, Princess Margaret Cancer Centre
Endocrine Oncology Site Group Head, Toronto General Hospital
Professor, Medicine and Oncology, University of Toronto
Shereen Ezzat, MD, is an Endocrine Oncologist at University Health Network and Professor in the Department of Medicine at the University of Toronto. A Clinician-Scientist with a focus on Endocrine Oncology, his research aims to identify the basis for development of endocrine tumors, to improve diagnostic tests and to identify targets for therapy of those diseases. He has published more than 200 scientific articles and has contributed 30 book chapters on endocrine oncology. He has given over 200 invited lectures to national and international scientific audiences and has received many awards from national and international scientific and other organizations, including the 2014 Maureen Coleman Award of the Carcinoid Neuroendocrine Tumor Society (2014), the Distinguished Service Award of the Canadian Society of Endocrinology & Metabolism (2012), an Endocrine Society Outstanding Abstract Award (2012), the Royal College of Physicians/CSCI Distinguished Scientist Award (2008), the Endocrine Society Abbott Research Mentor Award (2006), the Novartis Senior Investigator Award of the Clinical Research Society (2006) and the Gentle Giant Award of the Pituitary Network Association (2006).
As a passionate advocate for awareness, earlier diagnosis and better treatment of patients with endocrine tumors, Dr. Ezzat has mentored many young physicians who are now involved in the practice of the discipline. To ensure public knowledge and patient involvement, he was instrumental in the founding of the Pituitary Network Association and serves as a consultant to several patient groups.
Our lab studies the mechanisms of cancer development in hormone-producing glands (endocrine tumours) including those arising from the thyroid, pituitary, endocrine pancreas and adrenal glands.
We are interested in the mechanisms leading to the transcriptional and epigenetic regulation of tumour-derived growth and survival signals. Our focus is on members of the fibroblast growth factor (FGF) family of receptor tyrosine kinases which play an important role in sporadic and familial forms of these diseases. Signalling emphasis is on non-classical heterophilic interactions with cell adhesion molecules.
Research location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cancer
Secondary Research Area: Molecular & Cell Biology